The OPV protein are considered to be the essential proteins for replication, and is noted that these proteins are highly conserved in MCV when undergoing transcription. There are twenty MCV proteins with OPV counterparts that have their own homologs, and some even have their own functional motifs. Despite other factors, the physical order and regulation of essential ancestral poxvirus genes have been largely conserved in these MCV’s and OPV’s.
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